93.5% of Dogs’ Quality-of-Life Score Improved!

4CYTE EPIITALIS® FORTE, a novel nutraceutical, in the management of naturally occurring osteoarthritis in dogs.

Epiitalis® – Biota orientalis extract:

Patented for cartilage regeneration and repair in most parts of the world including Aus Pat: 2008336268 (anti- inflammatory) Aus Pat: 2008336267 (Chondroproliferative) USA Pat: 8431169 Chondroproliferative) EU;NZ;China; Canada

Pearson, W., Orth, M., Karrow, N., and Lindinger, M.I. (2008) Effects of simulated digests of Biota orientalis and a dietary nutraceutical on interleukin-1- induced inflammatory responses in cartilage explants. Am. J. Vet. Res. 69, 1560-1568


Research evaluating Aquamin™ has spanned 15 years and includes published in vitro, numerous in vivo animal studies and human trials. This portfolio of research has been conducted independently, and largely at academic institutions across the world, by investigators that are renowned in their respective fields.

Human Bone Trials:

2014 Impact Factor – Journal of Nutrition – 3.875

Slevin MM, Allsopp PJ, Magee PJ, et al. Supplementation with calcium and short-chain fructo-oligosaccharides affects markers of bone turnover but not bone mineral density in postmenopausal women. J Nutr. 2014;144(3):297-304.

2014 Impact Factor – Medicine and Science in Sports and Exercise – 3.983

Shea KL, Barry DW, Sherk VD, et al. Calcium supplementation and parathyroid hormone response to vigorous walking in postmenopausal women. Med Sci Sports Exerc. 2014;46(10):2007-13.

Barry DW, Hansen KC, van Pelt RE, et al. Acute calcium ingestion attenuates exercise-induced disruption of calcium homeostasis. Med Sci Sports Exerc. 2011;43(4):617-23.

Human Inflammation Joint Trials:

2014 Impact Factor – Nutrition Journal – 2.6

Frestedt JL, Kuskowski MA, Zenk JL. A natural seaweed derived mineral supplement (Aquamin F) for knee osteoarthritis: a randomised, placebo controlled pilot study. Nutr J. 2009;8:7.

Frestedt JL, Walsh M, Kuskowski MA, Zenk JL. A natural mineral supplement provides relief from knee osteoarthritis symptoms: a randomized controlled pilot trial. Nutr J. 2008;7:9.

Ryan S, O’Gorman DM, Nolan YM (2011) Evidence that the marine-derived multi-mineral Aquamin has anti-inflammatory effects on cortical glial-enriched cultures. Phytother Res 25:765-767.

Joy Frestedt A Mini Review; Aquamin Research: Minerals from Red Algae Journal of Oceanography and Marine Research 2013

Proud major partner of the 2020/21 NCHA Futurity


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We'd just like to remind all those who are excited to use Interpath products that 4CYTE cannot be purchased through our site.

4CYTE is a vet-only animal joint health supplement, and is available only through your veterinary clinic.

If you're looking to buy our human product, Osteo-Restore, you've come to the right place! Purchase here.

DisclaimerThis is a global website and please be aware that various countries have different regulatory requirements.

This information should be read accordingly.

Always consult your veterinarian on the health of your animal.

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